Search results for "childhood adversitie"

showing 7 items of 7 documents

Early Parental Death and Risk of Psychosis in Offspring: A Six-Country Case-Control Study

2019

Evidence for early parental death as a risk factor for psychosis in offspring is inconclusive. We analyzed data from a six-country, case-control study to examine the associations of early parental death, type of death (maternal, paternal, both), and child’s age at death with psychosis, both overall and by ethnic group. In fully adjusted multivariable mixed-effects logistic regression models, experiencing early parental death was associated with 1.54-fold greater odds of psychosis (95% confidence interval (CI): 1.23, 1.92). Experiencing maternal death had 2.27-fold greater odds (95% CI: 1.18, 4.37), paternal death had 1.14-fold greater odds (95% CI: 0.79, 1.64), and both deaths had 4.4…

ESTUDO DE CASOSTRESSCHILDHOODlcsh:Medicinechildhood adversitiespsychosiParental Death0302 clinical medicinePsicosi en els infantsSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.Medicineearly parental deathpsychosisDolRACEGeneral MedicineInfants Salut mentalchildhood adversitieEsquizofrèniaMaternal deathHEALTHcase-controlearly bereavementDISORDERSOffspringDISADVANTAGEethnic minoritiesethnic minoritieArticleOdds03 medical and health sciencesBEREAVEMENTJournal ArticleMortalitatPsiquiatriaMortalityRisk factorSettore MED/25 - PsichiatriaMETAANALYSISmulti-countrybusiness.industryMORTALITYlcsh:RCase-control studyOdds ratiomedicine.diseaseConfidence interval030227 psychiatrypopulation-basedschizophreniaPsychoses in childrenbusiness030217 neurology & neurosurgeryBereavementDemographyJournal of Clinical Medicine
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Association of childhood adversities and home atmosphere with functioning in old age: the Helsinki birth cohort study

2019

Objectivechildhood adversities have been linked with adverse health outcomes, but less is known about the long-term consequences of childhood home atmosphere. We investigated whether childhood adversities and home atmosphere were associated with physical and mental functioning in older age.Methodsin the Helsinki Birth Cohort Study 2003, participants born in the year 1934–44 had data available on nine childhood home atmosphere items, e.g. whether it was supportive and warm (sum score ranged between 0 and 36, higher score indicating better atmosphere), and nine childhood adversities, e.g. unemployment and divorce (sum score 0–9, coded into no; one; and two or more adversities) assessed in 200…

MaleAgingHealth Statusmental functioningchildhood adversitiesPhysical functionolder people0302 clinical medicinePhysical functioningAdverse Childhood ExperiencesSurveys and QuestionnairesActivities of Daily LivingPsychologyMedicine030212 general & internal medicineParent-Child RelationsFinlandta3142General MedicineMiddle AgedMental HealthFemalehealthy ageingBirth cohortpsyykkinen toimintakykyikääntyneetelinolotfyysinen toimintakykyShort form 36home atmosphereHealth outcomesArticle03 medical and health sciencesHumansphysical functioningAssociation (psychology)Geriatric AssessmentAgedMental functioningbusiness.industrylapsuuskasvuympäristöMental healthkotiympäristöikääntyminenSocioeconomic FactorsGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryDemographyAge and Ageing
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The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI)

2020

Funder: FP7 Ideas: European Research Council; doi: http://dx.doi.org/10.13039/100011199; Grant(s): HEALTH-F2-2010-241909

MaleHealth (social science)EpidemiologyEthnic groupEthnic GroupGene-environment interactionsEnvironment–environment interactions0302 clinical medicineEpidemiologyEthnicity10. No inequalityFirst episodeRISKbiologyIncidence (epidemiology)IncidenceCANNABISMiddle AgedCase-controlFirst-episode psychosis3. Good healthEuropePsychiatry and Mental healthCase–control Environment–environment interactions EU-GEI First-episode psychosis Gene–environment interactions IncidenceCase–control; EU-GEI; Environment–environment interactions; First-episode psychosis; Gene–environment interactions; IncidenceSchizophreniaCohortFemalePsychologyCase-Control StudieCase–controlBrazilHumanAdultmedicine.medical_specialtySocial PsychologyAdolescentStudy Protocols and SamplesDISORDERSEnvironment–environment interactionRepresentativeness heuristicEU-GEIGene–environment interactions03 medical and health sciencesYoung AdultPSYCHOSISAGEFirst-episode psychosiEnvironment-environment interactionsmedicineHumansGene–environment interactionSettore MED/25 - PsichiatriaMETAANALYSISbiology.organism_classificationmedicine.disease030227 psychiatryCase-Control StudiesSchizophreniaGene-Environment InteractionCannabisCHILDHOOD ADVERSITIES030217 neurology & neurosurgeryDemographySocial Psychiatry and Psychiatric Epidemiology
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Estimating Exposome Score for Schizophrenia Using Predictive Modeling Approach in Two Independent Samples: The Results From the EUGEI Study

2019

The EUGEI project was supported by the grant agreement HEALTH-F2-2010-241909 from the European Community’s Seventh Framework Programme. The authors are grateful to the patients and their families for participating in the project. They also thank all research personnel involved in the GROUP project, in particular J. van Baaren, E. Veermans, G. Driessen, T. Driesen, E. van’t Hag and J. de Nijs. Bart PF Rutten was funded by a VIDI award number 91718336 from the Netherlands Scientific Organisation.

MalecannabisLogistic regression0302 clinical medicineLasso (statistics)Adverse Childhood ExperiencesStatisticsOdds RatioChild AbusePOLYGENIC RISKpsychosisChildPsychiatrySUMMER BIRTHFramingham Risk Score3. Good healthExposomePsychiatry and Mental healthmachine learningSchizophreniaArea Under CurveFemaleMarijuana UseSeasonsEnvironment And Schizophrenia—Feature Editor: Jim van OsLife Sciences & Biomedicineenvironmentpredictive modelingAdultExposomeDISORDERSrisk scoreYoung Adult03 medical and health sciencesPSYCHOSISmedicineJournal ArticleHumansHearing LossMETAANALYSISDEFICIT SCHIZOPHRENIAENVIRONMENTModels StatisticalScience & Technologychildhood traumaReceiver operating characteristicbusiness.industrySiblingsBullyingBayes TheoremChild Abuse SexualOdds ratiohearing impairmentmedicine.disease030227 psychiatryschizophreniaLogistic ModelsROC CurveSexual abuseCase-Control StudiesbusinessCHILDHOOD ADVERSITIES030217 neurology & neurosurgerywinter birth
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Perceived major experiences of discrimination, ethnic group, and risk of psychosis in a six-country case-control study

2021

AbstractBackgroundPerceived discrimination is associated with worse mental health. Few studies have assessed whether perceived discrimination (i) is associated with the risk of psychotic disorders and (ii) contributes to an increased risk among minority ethnic groups relative to the ethnic majority.MethodsWe used data from the European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 2, a population-based case−control study of incident psychotic disorders in 17 catchment sites across six countries. We calculated odds ratios (OR) and 95% confidence intervals (95% CI) for the associations between perceived discrimination and psychosis using mixed-…

Mediation (statistics)LIFE EVENTSMIGRATIONPopulationEthnic groupLogistic regressionpsychosiOdds03 medical and health sciences0302 clinical medicineMINORIAS ÉTNICASSCHIZOPHRENIAMedicinepsychosisfirst-episodeeducationCase−controlApplied PsychologyTRAUMACase-control discrimination first-episode minority ethnic group multi-country psychosis psychotic disorderFirst episodemulti-countryeducation.field_of_studyminority ethnic groupCONSEQUENCESbusiness.industryAbsolute risk reductionPATHWAYSOdds ratiopsychotic disorderCase-controlMEDIATION ANALYSIS030227 psychiatryPsychiatry and Mental health[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]HEALTHbusinessCHILDHOOD ADVERSITIES030217 neurology & neurosurgeryDemographydiscrimination
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Childhood adversity, bonding and family functioning – is there a specific association with borderline personality disorder in adolescents?

2014

Objective: Despite growing evidence on risk-factors of borderline personality disorder (BPD) in adults, there is a paucity of research on such specific characteristics of BPD in youth. Furthermore, studies on adolescence BPD in clinical setting are still rare. This study aimed to investigate adverse childhood experiences, parental bonding and family functioning in a sample of female adolescent inpatients with BPD, and to compare them with a clinical control group with mixed psychiatric diagnoses. Method: A consecutive sample of 91 female adolescents inpatients (ages 12-18 years) was recruited within a psychiatric university hospital. BPD was assessed using the Structured Clinical Interview …

borderline adolescents childhood adversities Family functioning
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Deconstructing and reconstructing resilience: a dynamic network approach

2019

Resilience is still often viewed as a unitary personality construct that, as a kind of anti-nosological entity, protects individuals against stress-related mental problems. However, increasing evidence indicates that the maintenance of mental health in the face of adversity results from complex and dynamic processes of adaptation to stressors that involve the activation of several separable protective factors. Such resilience factors can reside at biological, psychological and social levels and may include stable predispositions (such as genotype or personality traits) and malleable properties, skills, capacities or external circumstances (such as gene expression patterns, emotion regulatio…

emotion regulationDynamic network analysisDISORDERSmedia_common.quotation_subjectEmotionsIndividualitySUSCEPTIBILITYModels Psychological050105 experimental psychology03 medical and health sciencesSocial supportstress0302 clinical medicineAdaptation Psychologicaldynamic systemPersonalityHumans0501 psychology and cognitive sciencesBig Five personality traitsresilienceGeneral Psychologymedia_commonTRAUMATIC EVENTSConceptualizationCUMULATIVE LIFETIME ADVERSITYMEDIAL PREFRONTAL CORTEXMental Disorders05 social sciencesStressorResilience PsychologicalanxietyMental healthPREVALENCEsymptom networkdepressionnetworkPsychological resiliencePsychologyCOMORBIDITYCHILDHOOD ADVERSITIES030217 neurology & neurosurgeryStress Psychologicalmental healthCognitive psychology
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